A retrospective study of the prognostic value of MRI-derived residual tumors at the end of intensity-modulated radiotherapy in 358 patients with locally-advanced nasopharyngeal carcinoma

Table 4 Summary of multivariate analysis of prognostic factors in patients with NPC

End point	Variable	Regression coefficient	Standard error	HR	95% CI		P -value
End point	Variable	Regression coefficient	Standard error	HR	Lower	Upper	P -value
OS	Age	0.84	0.25	2.32	1.412	3.79	0.001
	N-stage	0.36	0.14	1.43	1.10	1.87	0.008
	Residual tumor	0.75	0.26	2.11	1.26	3.54	0.004
LRFS	Age	1.57	0.50	4.80	1.78	12.83	0.002
LRFS	Residual tumor	1.59	0.51	4.88	1.81	13.16	0.002
DFS	Age	0.59	0.22	1.81	1.17	2.80	0.007
	N-stage	0.23	0.12	1.26	1.01	1.58	0.049
	Residual tumor	0.65	0.23	1.91	1.23	2.98	0.004

HR: hazard ratio; CI, confidence interval; P-values were calculated using an adjusted Cox proportional hazards model. OS: overall survival; LRFS: local relapse-free survival; DFS: disease-free survival.
The variables were stratified as following: Age: < 50 y vs ≥ 50 y; N-stage: N0 vs N1vs N2 vs N3; T-stage: T3 vs T4; Residual tumor: having tumor vs no tumor. The table presents only the data with statistical significances.

ISSN: 1748-717X