Radiation Oncology

Table 1 Patient characteristics per treatment groups

From: Comparison of radiation regimens in the treatment of Glioblastoma multiforme: results from a single institution

	Patients (n = 276)
	60 Gy in 30 Fr		60 Gy in 20 Fr		40 Gy in 15 Fr		*P value*
	(n = 147)		(n = 86)		(n = 43)
	Number	%	Number	%	Number	%
Age
<65	114	77.6	68	79.1	8	18.6	<.0001
≥65	33	22.4	18	20.9	35	81.4
median	59		57		72
Sex
Female	55	37.4	34	39.5	20	46.5	0.562
Male	92	65.6	52	60.5	23	53.5
KPS
<70	7	4.7	10	11.6	20	46.5	<.0001
≥70	140	95.3	76	88.4	23	53.5
Focality
Multifocal	12	8.2	8	9.3	8	18.6	0.130
Unifocal	135	91.8	78	90.7	35	81.4
Extent of surgery
Biopsy	12	8.1	17	19.7	8	18.6	0.017
STR	98	66.6	45	52.3	30	63.7
GTR	37	25.1	24	27.9	5	11.6
Chemotherapy
Yes	141	95.2	85	98.8	24	55.8	<.0001
No	4	2.7	1	1.2	16	37.2
Unknown	2	1.3	0	0	3	6.9
Repeat surgery
Yes	49	33.3	20	23.2	2	4.6	0.001
No	98	66.7	66	76.7	41	93.4
MGMT
Methylated	60	40.8	25	29	16	37.2	0.031
Unmethylated	53	36.0	38	44.1	9	20.9
Unknown	34	23.2	23	26.7	18	41.8

Abbreviations: Fr Fractions, STR Subtotal resection, GTR Gross total resection, MGMT O6-methylguanine-DNA methyltransferase.

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