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Figure 1 | Radiation Oncology

Figure 1

From: Prospective longitudinal assessment of parotid gland function using dynamic quantitative pertechnate scintigraphy and estimation of dose–response relationship of parotid-sparing radiotherapy in head-neck cancers

Figure 1

Reframed dynamic images (1 minute per frame) showing increasing uptake in the salivary glands and subsequent washout after sialogogue administration halfway through the study. (a): Regions of interest drawn around major salivary glands (b) with background correction performed using the midline neck region. Typical pre-treatment time-acitivty curves (c) for right and left parotid glands. Note the steady and progressive increase in uptake immediately following injection of 99mTc-pertechnate. Stimulation of salivary secretion by sialogogue (15-minutes post-injection) leads to decline in detectable counts within the glands. Percentage uptake and relative uptake of individual parotid gland (d). Salivary excretion fraction (SEF) is quantified by calculating maximal excretory activity per gland as a fraction of its maximal uptake (d).

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