Table 4 Predictors of anastomotic stenosis in patients with distal esophageal or esophago-gastric junction cancer treated with neoadjuvant chemoradiation followed by transhiatal esophagectomy

Age

0.96

0.90-1.01

0.14

0.99

0.92-1.06

0.66

BMI

0.99

0.87-1.14

0.92

Co-morbidity:

 0

4.82

1.10-21.19

0.04

3.17

0.54-18.82

0.20

 1

1.71

0.77-6.24

0.41

1.39

0.34-5.67

0.64

 2 or more

ref

Cardiovascular co-morbidity:

 No

2.73

0.89-8.33

0.78

 Yes

ref

Pulmonary co-morbidity:

 No

ref

 Yes

0.96

0.23-4.06

0.96

ASA classification:

 I

1.16

0.25-5.72

0.85

 II

ref

 III

0.39

0.04-4.03

0.43

Histology:

 Adenocarcinoma

ref

 Squamous cell carcinoma

1.23

0.16-9.43

0.84

Mean dose

1.00

1.00-1.00

0.50

V20

1.00

0.98-1.03

0.81

V25

1.01

0.99-1.03

0.24

V30

1.01

0.99-1.03

0.28

V35

1.01

0.99-1.03

0.27

V40

1.01

0.99-1.03

0.21

OR time

1.00

0.99-1.01

0.87

Resection type:

 Open

1.61

0.53-4.88

0.40

 Laparoscopic

ref

Method of anastomosis:

 EE continuous

ref

 EE interrupted

2.10

0.51-8.57

0.30

 Side-to -side stapler

0.34

0.06-1.90

0.22

Interval last RT- surgery

0.88

0.74-1.04

0.14

0.92

0.77-1.11

0.39

Anastomotic leakage

1.58

0.45-5.55

0.48