Table 3 Predictors of anastomotic leakage in patients with distal esophageal or esophago-gastric junction cancer treated with neoadjuvant chemoradiation followed by transhiatal esophagectomy

Age

0.99

0.93-1.05

0.63

BMI

1.07

0.91-1.24

0.42

Co-morbidity:

 0

0.80

0.16-3.94

0.78

 1

0.76

0.18-3.26

0.71

 2 or more

ref

Cardiovascular co-morbidity:

 No

1.29

0.37-4.53

0.69

 Yes

ref

Pulmonary co-morbidity:

 No

ref

 Yes

1.7

0.36-8.04

0.50

ASA classification:

 I

2.13

0.43-10.68

0.36

 II

ref

 III

1.19

0.11-12.82

0.89

Histology:

 Adenocarcinoma

ref

 Squamous cell carcinoma

0.98

0.10-10.83

0.98

Mean dose

1.00

1.00-1.00

0.07

1.00

1.00-1.00

0.67

V20

0.97

0.96-1.00

0.03

0.96

0.90-1.02

0.21

V25

0.99

0.97-1.01

0.23

V30

0.99

0.98-1.01

0.25

V35

0.99

0.97-1.01

0.28

V40

0.99

0.97-1.01

0.32

OR time

0.99

0.97-1.01

0.25

Resection type:

 Open

2.17

0.61-7.71

0.23

 Laparoscopic

ref

Method of anastomosis:

 EE continuous

ref

 EE interrupted

2.57

0.57-11.69

0.22

 Side-to -side stapler

2.25

0.44-11.65

0.33

Interval last RT- surgery

1.00

0.83-1.20

0.99