Figure 4
From: Acute adaptive immune response correlates with late radiation-induced pulmonary fibrosis in mice
Strain dependent serum cytokine levels in acute radiation response. Serum was collected from mice at 6 hours, 1 day and 7 days post-irradiation. A) Cytokine concentrations measured using the Multiplex assay. Results are presented as mean ± SE for groups of n = 4-5 mice. Significant variation in inbred strain measures by ANOVA indicated. B) Pearson correlation of late disease phenotypes with serum cytokine levels (R = 0.76, p = 0.07 between percent fibrosis and Il10 concentration at 6 hours; R = 0.81, p = 0.04 between survival time and control Il17 concentration).