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Table 1 Studies assessing complication rates from fiducial marker implantation for prostate image guided radiotherapy

From: Infections after fiducial marker implantation for prostate radiotherapy: are we underestimating the risks?

Study

Patient numbers

Infective complications

Gill et al. [1]

234

3 patients (1.3%) required admission for sepsis

1 patient (0.4%) had Grade 4 septicaemia.

Langenhuijsen et al. [2]

209

4 patients (1.9%) with fever received additional antibiotics.

There were no hospital admissions.

Igdem et al. [3]

135

3 patients (2.2%) developed symptomatic urinary infection with fever and received antibiotics.

There were no hospital admissions.

1 (0.7%) patient developed asymptomatic bacteriuria resistant to antibiotic therapy.

Moman et al. [4]

402 had transrectal FM implantation

2 (0.5%) developed urosepsis (Grade 3 toxicity)

512 had transperineal FM implantation

No grade 3 or 4 toxicity.

Loh et al.

285

22 patients (7.7%) received antibiotic treatment for a urinary infection

8 patients (2.8%) required hospital admission for urosepsis.

TRUS biopsy series

  

Wagenlehner et al. [10]

521

5.2% had symptomatic urinary tract infection

3.1% required hospital admissions for infectious complications

  1. FM = fiducial marker.
  2. TRUS = Transrectal ultrasound guided.