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Table 1 Size, zeta potential and entrapment efficiency for Magnevist in liposomal formulations

From: Cellular uptake and in vitro antitumor efficacy of composite liposomes for neutron capture therapy

Formulation (mol%)

Diameter [nm] ± SD

Zeta potential [mV] ± SD

Encapsulation efficiency [%]

Gd concentration per well [mg/ml]

DOPC-Chol-DOTAP (57:33:9)

136.20 ± 8.07

41.25 ± 2.49

10.24 ± 4.85

0.47

DOPC-Chol-CL (70:20:10)

152.11 ± 10.22

−67.77 ± 2.70

6.56 ± 1.74

0.27

DOPC-Chol-DOPE (70:20:10)

133.19 ± 5.76

−15.53 ± 7.53

9.37 ± 2.83

0.36

DOPC-Chol-FolPEG 2000 (63:37:0.13)

136.77 ± 8.81

−24.70 ± 3.10

9.60 ± 1.75

0.36

DOPC-DOPE (50:50)

138.54 ± 10.17

−17.78 ± 6.04

10.21 ± 2.53

0.46