Time-dependent uptake of liposomal gadolinium formulations (DOTAP and DOPC-DOPE) and Magnevist into F98 cells. Gd-concentration in (A) F98 and (B) LN229 cells after incubation with liposomal Magenvist formulations, i.e. DOPC-DOPE and DOTAP (1 mg lipid/ml, respective Gd-concentration cf. Table 1) and Magnevist (0.34 mg Gd/ml) for 1 to 24 h. Gd-concentration was determined via ICP-MS. Results are arithmetic means, error bars represent SD, n = 3.