Figure 2

Single hemispheric Gamma Knife irradiation with 30 Gy leads to no injury on T2-weighted imaging. The single hemispheric irradiation plan (blue line is 50% isodose, green line is 25%, and yellow line is 12.5% isodose, approximately) was exactly the same in the 50 Gy and the 30 Gy mouse model. The majority of the contralateral lesion seen at 12 weeks in the mice irradiated at 50 Gy received less than 12.5 Gy. For comparison, T2-weighted images are also included of the same representative mouse as Figure 1 at week one and week 12 post-irradiation (PIR).