Figure 1

Serum amyloid A (SAA) rises in select patients during thoracic radiation. A) Average SAA rose during thoracic radiation and returned to pre-treatment levels after radiotherapy was complete. B) Individual patients showed heterogeneity in the response of SAA during thoracic radiation. Green lines show patients with increased levels of SAA after 10 days of radiotherapy. Red lines show patients with decreased levels of SAA after 10 days of radiotherapy. Yellow lines show patients with no change in SAA after 10 days of radiotherapy. Dashed line shows upper limit of normal values for SAA (2000 ng/ml). Data plotted on log scale to highlight the three orders of magnitude spread in the range of values. C) c-Reactive Protein (cRP) showed an elevated trend during radiation but similarly returned to pre-treatment levels after radiotherapy. D) Individual patients showed heterogeneity in the response of cRP during thoracic radiation. Green lines show patients with increased levels of cRP after 10 days of radiotherapy. Red lines show patients with decreased levels of cRP after 10 days of radiotherapy. Yellow lines show patients with no change in cRP after 10 days of radiotherapy. Dashed line shows upper limit of normal values for cRP (10 μg/ml). Data in (a) and (c) are plotted as mean ± SEM. *p < 0.05.