|
Type of toxicity
|
RT (n = 36), n
|
CCRT (n = 27), n
|
p
value
*
|
|---|
|
Grade 1
|
Grade 2
|
Grade 3
|
Grade 4
|
Grade 1
|
Grade 2
|
Grade 3
|
Grade 4
|
|---|
|
Hematological
| | | | | | | | | |
|
Leukopenia
|
7
|
9
|
2
|
0
|
8
|
10
|
2
|
0
|
0.094
|
|
Neutropenia
|
2
|
3
|
1
|
0
|
9
|
2
|
0
|
1
|
0.034
|
|
Anemia
|
9
|
6
|
1
|
1
|
9
|
7
|
0
|
0
|
0.482
|
|
Thrombocytopenia
|
7
|
3
|
2
|
0
|
8
|
6
|
3
|
0
|
0.019
|
|
Non-hematological
| | | | | | | | | |
|
Hyperbilirubinemia
|
2
|
0
|
0
|
0
|
2
|
1
|
0
|
0
|
0.406
|
|
Elevated ALT
|
2
|
0
|
0
|
0
|
6
|
0
|
0
|
0
|
0.051
|
|
Elevated AST
|
2
|
0
|
0
|
0
|
2
|
1
|
0
|
0
|
0.406
|
|
Nausea/Vomiting
|
13
|
1
|
0
|
0
|
8
|
1
|
0
|
0
|
0.686
|
|
Diarrhea/Constipation
|
5
|
1
|
0
|
0
|
3
|
2
|
0
|
0
|
0.793
|
-
*Mann–Whitney U test, two-tailed.
-
RT radiotherapy, CCRT concurrent chemoradiotherapy, ALT alanine aminotransferase, AST aspartate aminotransferase.
