Intensity modulated radiotherapy for locally advanced and metastatic pancreatic cancer: a mono-institutional retrospective analysis

Table 3 Comparison of toxicities between RT and CCRT groups

Type of toxicity	RT (n = 36), n				CCRT (n = 27), n				p value ^*
Type of toxicity	Grade 1	Grade 2	Grade 3	Grade 4	Grade 1	Grade 2	Grade 3	Grade 4	p value ^*
Hematological
Leukopenia	7	9	2	0	8	10	2	0	0.094
Neutropenia	2	3	1	0	9	2	0	1	0.034
Anemia	9	6	1	1	9	7	0	0	0.482
Thrombocytopenia	7	3	2	0	8	6	3	0	0.019
Non-hematological
Hyperbilirubinemia	2	0	0	0	2	1	0	0	0.406
Elevated ALT	2	0	0	0	6	0	0	0	0.051
Elevated AST	2	0	0	0	2	1	0	0	0.406
Nausea/Vomiting	13	1	0	0	8	1	0	0	0.686
Diarrhea/Constipation	5	1	0	0	3	2	0	0	0.793

^*Mann–Whitney U test, two-tailed.
RT radiotherapy, CCRT concurrent chemoradiotherapy, ALT alanine aminotransferase, AST aspartate aminotransferase.

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