Is elective inguinal radiotherapy necessary for locally advanced rectal adenocarcinoma invading anal canal?

Radiation Oncology

Table 4 Salvage outcomes of patients with IGN recurrence

No	Isolated IGN recurrence	Synchronously recurrent sites	Laterality of IGN recurrence	Time to IGN recurrence (months)	Survival after IGN recurrence (months)	Last status
1	Yes		Bilateral	8	120	NED
2	Yes		Unilateral	61	63	Dead^*
3	Yes		Unilateral	20	61	AWD
4	No	Brain	Bilateral	29	5	DWD
5	No	LPN, PAN	Bilateral	30	21	DWD
6	No	LPN, PAN	Unilateral	28	22	DWD
7	No	PAN	Unilateral	19	11	DWD
8	No	Tumor bed, lung	Unilateral	36	20	DWD
9	No	LPN, PAN	Bilateral	10	11	DWD
10	No	LPN, seeding	Unilateral	105^†	8	DWD

Abbreviations: IGN inguinal node, LPN lateral pelvic node, PAN para-aortic node, NED no evidence of disease, AWD alive with disease, DWD dead with disease.
^*IGN recurrence was successfully salvaged with concurrent CRT, but endometrial cancer developed 31 months after IGN recurrence that progressed to lung metastasis and peritoneal seeding causing death.
^†Recurrence developed initially in the tumor bed at 93 months and non-isolated IGN recurrence occurred 1 year later.

ISSN: 1748-717X