Table 3 Multivariate analysis in relation to overall survival and disease-free survival
Patient characteristics | Overall survival | Disease-free survival | ||||
|---|---|---|---|---|---|---|
HR | 95%CI | P-value | HR | 95%CI | P-value | |
Tumor stage before CRT | ||||||
II | ||||||
III | 3.846 | 0.502-29.465 | 0.195 | 2.045 | 0.724-5.778 | 0.177 |
NLR before CRT | ||||||
Low (<2.8) | ||||||
High (≥2.8) | 2.123 | 1.140-3.954 | 0.018 | 1.363 | 0.840-2.214 | 0.210 |
CEA, ng/ml | ||||||
<5 | ||||||
≥5 | 1.364 | 0.698-2.665 | 0.363 | 1.427 | 0.876-2.324 | 0.153 |
Surgical procedure | ||||||
Curative surgery | ||||||
Palliative surgery | 1.289 | 0.488-3.401 | 0.608 | 1.472 | 0.680-3.185 | 0.327 |
Lymphatic or vascular invasion | ||||||
No | ||||||
Yes | 1.419 | 0.618-3.257 | 0.409 | 1.368 | 0.712-2.629 | 0.347 |
ypTNM staging | ||||||
ypT0-2 N0 | ||||||
ypT3-4/N+ | 3.928 | 1.651-9.345 | 0.002 | 3.477 | 1.857-6.509 | <0.001 |
TRG score | ||||||
0-1 | ||||||
2-3 | 0.904 | 0.464-1.760 | 0.766 | 1.027 | 0.626-1.684 | 0.916 |
Adjuvant chemotherapy | ||||||
Yes | ||||||
No | 3.506 | 1.251-9.827 | 0.017 | |||