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Table 1 Patient characteristics

From: Baseline neutrophil-lymphocyte ratio (≥2.8) as a prognostic factor for patients with locally advanced rectal cancer undergoing neoadjuvant chemoradiation

Variables

N (%)

Low NLR (%)

High NLR(%)

P-value

Gender

    

Female

50 (25.1)

35 (70.0)

15 (30.0)

 

Male

149 (74.9)

98 (65.8)

51 (34.2)

0.583

Age, years

    

<60

135 (67.2)

90 (66.7)

45 (33.3)

 

≥60

64 (31.8)

43 (67.2)

21 (32.8)

0.942

Tumor stage before CRT

   

II

26 (13.1)

23 (88.5)

3 (11.5)

 

III

173 (86.9)

110 (63.6)

63 (36.4)

0.012

Tumor location

    

Low

122 (61.3)

82 (67.2)

40 (32.8)

 

Middle-high

77 (38.7)

51 (66.2)

26 (33.8)

0.886

CEA, ng/ml

    

<5

110 (55.3)

77 (70.0)

33 (30.0)

 

≥5

89 (44.7)

56 (62.9)

33 (37.1)

0.292

RT dose, Gy

    

45-50

122 (61.3)

76 (62.3)

46 (37.7)

 

>50

77 (38.7)

57 (74.0)

20 (26.0)

0.087

Surgical procedure

    

APR

115 (57.8)

81 (70.4)

34 (29.6)

 

LAR

70 (35.2)

45 (64.3)

25 (35.7)

 

Hartmann

14 (7.0)

7 (50.0)

7 (50.0)

0.246*

ypTNM staging

    

ypT0-2 N0

88 (44.2)

62 (70.5)

26 (29.5)

 

ypT3-4 or N+

111 (55.8)

71 (64.0)

40 (36.0)

0.334

TRG score

    

0-1

117 (58.8)

82 (70.1)

35 (29.9)

 

2-3

82 (41.2)

51 (62.2)

31 (37.8)

0.245

Adjuvant chemotherapy

   

Yes

184 (92.5)

121 (65.8)

63 (34.2)

 

No

15 (7.5)

12 (80.0)

3 (20.0)

0.393*

  1. (*Fisher’s exact test).