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Table 2 Characteristics of patients with radiation-induced brachial plexus neuropathy

From: Dosimetric analysis of the brachial plexus among patients with breast cancer treated with post-mastectomy radiotherapy to the ipsilateral supraclavicular area: report of 3 cases of radiation-induced brachial plexus neuropathy

Characteristic

Patient 1

Patient 2

Patient 3

Tumor location

Left breast

Left breast

Right breast

Staging of the primary tumor (AJCC 2008)

T2N2M0

T1N3M0

T3N3M0

Surgeries

MRM and ALND

MRM and ALND

MRM and ALND

Chemotherapy

6 courses of DCE

6 courses of CEF

6 courses of CEF

Endocrine therapy

-

TAM

TAM

Onset of symptoms after radiotherapy

35 months

27 months

29 months

Symptom occurrence to seeking care

7 months

12 months

10 months

Initial symptoms

Sensory disorders

Motor deficits

Motor deficits

Overall symptoms

Pain, sensory disorders

Motor deficits, pain, sensory disorders

Motor deficits, pain, sensory disorders

Localization of injury

C5-Th1

C5-7

C5-Th1

Severity of injury (LENT-SOMA scale)

Grade 2

Grade 2

Grade 3

Upper-extremity edema

Yes

No

No

Time of treatment

27 months

31 months

12 months

Treatment outcome

Stable

Slow progression

Slow progression

  1. MRM: modified radical mastectomy; ALND: axillary lymph node dissection; DCE: docetaxel, cyclophosphomide, epirubicin; CEF: cyclophosphamide, epirubicin, 5-fluorouracil; LENT-SOMA: late effects of normal tissue-subjective, objective, management, and analytic.