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Table 1 Characteristics of breast cancer patients who received and did not receive postmastectomy radiotherapy

From: Number of negative lymph nodes can predict survival of breast cancer patients with four or more positive lymph nodes after postmastectomy radiotherapy

Characteristic

n

Without PMRT

With PMRT

p

(n = 234) (%)

(n = 371) (%)

Age, years

  <35

64

20 (8.6)

44 (11.9)

0.197

  ≥35

541

214 (91.4)

327 (88.1)

 

Menopausal status

  Premenopausal

400

153 (65.4)

247 (66.6)

0.763

  Postmenopausal

205

81 (34.6)

124 (33.4)

 

Tumor size

  T1-T2

471

189 (80.8)

282 (76.0)

0.170

  T3-T4

134

45 (19.2)

89 (24.0)

 

Nodal stage

  N2

321

139 (59.4)

182 (49.1)

0.013 *

  N3

284

95 (40.6)

189 (50.9)

 

ER status

  Negative

285

112 (47.9)

173 (46.6)

0.767

  Positive

320

122 (52.1)

198 (53.4)

 

PR status

  Negative

229

92 (39.3)

137 (36.9)

0.555

  Positive

376

142 (60.7)

234 (63.1)

 

HER2 status

  Negative

376

136 (58.1)

240 (64.7)

0.105

  Positive

229

98 (41.9)

131 (35.3)

 

Breast cancer subtype

  Luminal A

295

107 (45.7)

188 (50.7)

0.368

  Luminal B

130

53 (22.6)

77 (20.8)

 

  HER2 positive

99

45 (19.3)

54 (14.5)

 

  Triple negative

81

29 (12.4)

52 (14.0)

 

Number of NLNs

  0-12

477

180 (76.9)

297 (80.0)

0.358

  12-39

128

54 (23.1)

74 (20.0)

 

LNR

  < 0.20

42

29 (12.4)

13 (3.5)

< 0.001*

  0.21-0.65

337

131 (56.0)

206 (55.5)

 

  > 0.65

226

74 (31.6)

152 (41.0)

 
  1. PMRT, post-mastectomy radiotherapy; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor-2; NLNs, negative lymph nodes; LNR, lymph node ratio.
  2. *p < 0.05 indicates a significant difference.