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Table 2 Univariate analysis for patients with thyroid volume of at least 8 cc

From: Dosimetric predictors of hypothyroidism in oropharyngeal cancer patients treated with intensity-modulated radiation therapy

Variable

Euthyroid

Hypothyroid

p-Value

(n = 47)

(n = 60)

Gender

  

0.222

  F

3

9

 

  M

44

51

Age (y), mean; [SD]

60.3 [8.2]

57.8 [10.8]

0.161

Weight (lbs), mean; [SD]

183 [35.7]

178 [38.4]

0.461

T Stage

  

0.201

  1

12

14

 

  2

24

22

  3

8

18

  4

3

6

N Stage

  

0.771

  0

3

7

 

  1

10

7

  2

30

45

  3

4

1

Neck Dissection

  

0.292

  No

42

48

 

  Yes

5

12

Chemo

  

1.002

  No

8

10

 

  Yes

39

50

Follow-up time (m), mean; [SD]

52.1 [30.3]

57.0 [24.9]

0.231

Thyroid volume (cc), mean; [SD]

15.6 [15.5]

13.1 [4.6]

0.491

Mean dose (Gy), mean; [SD]

52.8 [11.7]

57.8 [7.3]

0.0481

V10 (%), mean; [SD]

97.4 [12.1]

99.7 [2.5]

0.0481

V20 (%), mean; [SD]

94.4 [16.3]

99.2 [4.3]

0.0381

V30 (%), mean; [SD]

91.7 [20.2]

98.2 [7.2]

0.0151

V40 (%), mean; [SD]

85.6 [24.4]

94.9 [13.5]

0.0671

V50 (%), mean; [SD]

70.9 [31.5]

84.2 [22.2]

0.0651

V60 (%), mean; [SD]

34.8 [31.3]

43.7 [28.8]

0.0751

V70 (%), mean; [SD]

2.86 [4.95]

7.1 [12.4]

0.0261

VS10 (cc), mean; [SD]

0.36 [1.53]

0.05 [0.39]

0.0481

VS20 (cc), mean; [SD]

0.75 [2.01]

0.108 [0.638]

0.0371

VS30 (cc), mean; [SD]

1.09 [2.51]

0.225 [0.976]

0.0161

VS40 (cc), mean; [SD]

1.89 [3.12]

0.683 [1.8]

0.0571

VS50 (cc), mean; [SD]

4.08 [4.72]

2.07 [3.03]

0.0481

VS60 (cc), mean; [SD]

9.83 [9.1]

7.38 [4.8]

0.101

VS70 (cc), mean; [SD]

15.2 [15.0]

12.2 [4.65]

0.191

  1. 1based on Mann–Whitney test.
  2. 2based on Fisher’s exact test.