Table 1 Patient clinicodemographic characteristics and laboratory findings
From: The role of radiotherapy in the management of POEMS syndrome
Characteristic | All (n = 33) | RT ( n = 13) | Non-RT ( n = 20) | |
|---|---|---|---|---|
No. of patients (%) | No. of patients (%) | No. of patients (%) | p value * | |
Median age, year (range) | 45 (25–68) | 51 (25–68) | 45 (28–63) | 0.592 |
Gender | ||||
Male | 24 (73) | 12 (92) | 12 (60) | 0.056 |
Female | 9 (27) | 1 (8) | 8 (40) | |
ECOG performance status | ||||
1 | 6 (18) | 2 (15) | 4 (20) | 0.451 |
2 | 11 (33) | 6 (46) | 5 (25) | |
3 | 16 (48) | 5 (39) | 11 (55) | |
Number of POEMS features | ||||
≤7 features | 19 (58) | 7 (54) | 12 (60) | 1.000 |
>7 features | 14 (42) | 6 (46) | 8 (40) | |
Type of M-protein | ||||
IgG | 17 (52) | 8 (62) | 9 (45) | 0.305 |
IgA | 13 (39) | 5 (38) | 8 (40) | |
IgG and IgA | 3 (9) | 0 (0) | 3 (15) | |
Type of plasma cell-proliferative disorder | ||||
OSM | 13 (39) | 8 (62) | 5 (25) | 0.067 |
CD | 4 (12) | 0 (0) | 4 (20) | 0.136 |
OSM + CD | 10 (30) | 5 (38) | 5 (25) | 0.461 |
VEGF elevation without gross lesion | 6 (18) | 0 (0) | 6 (30) | 0.060 |
Plasma cell component in bone marrow | ||||
≤5% | 20 (61) | 8 (62) | 12 (60) | 1.000 |
>5% | 13 (39) | 5 (38) | 8 (40) | |
Abnormal clonal plasma cells in bone marrow | ||||
Absent | 28 (85) | 13 (100) | 15 (75) | 0.131 |
Present | 5 (15) | 0 (0) | 5 (25) | |
Laboratory findings | ||||
ESR >20 mm/h | 16 (48) | 5 (38) | 11 (55) | 1.000 |
Hemoglobin <11 g/dL | 2 (6) | 0 (0) | 2 (10) | 0.508 |
Hemoglobin >16 g/dL | 5 (15) | 4 (31) | 1 (5) | 0.066 |
Platelets >450 x 103/μL | 11 (33) | 2 (15) | 9 (45) | 0.128 |
Creatinine clearance <60 mL/min | 5 (15) | 0 (0) | 5 (25) | 0.131 |