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Table 1 Patient clinicodemographic characteristics and laboratory findings

From: The role of radiotherapy in the management of POEMS syndrome

Characteristic All (n = 33) RT ( n = 13) Non-RT ( n = 20)  
No. of patients (%) No. of patients (%) No. of patients (%) p value *
Median age, year (range) 45 (25–68) 51 (25–68) 45 (28–63) 0.592
Gender     
 Male 24 (73) 12 (92) 12 (60) 0.056
 Female 9 (27) 1 (8) 8 (40)  
ECOG performance status     
 1 6 (18) 2 (15) 4 (20) 0.451
 2 11 (33) 6 (46) 5 (25)  
 3 16 (48) 5 (39) 11 (55)
Number of POEMS features     
 ≤7 features 19 (58) 7 (54) 12 (60) 1.000
 >7 features 14 (42) 6 (46) 8 (40)  
Type of M-protein     
 IgG 17 (52) 8 (62) 9 (45) 0.305
 IgA 13 (39) 5 (38) 8 (40)  
 IgG and IgA 3 (9) 0 (0) 3 (15)  
Type of plasma cell-proliferative disorder     
 OSM 13 (39) 8 (62) 5 (25) 0.067
 CD 4 (12) 0 (0) 4 (20) 0.136
 OSM + CD 10 (30) 5 (38) 5 (25) 0.461
 VEGF elevation without gross lesion 6 (18) 0 (0) 6 (30) 0.060
Plasma cell component in bone marrow     
 ≤5% 20 (61) 8 (62) 12 (60) 1.000
 >5% 13 (39) 5 (38) 8 (40)
Abnormal clonal plasma cells in bone marrow     
 Absent 28 (85) 13 (100) 15 (75) 0.131
 Present 5 (15) 0 (0) 5 (25)
Laboratory findings     
 ESR >20 mm/h 16 (48) 5 (38) 11 (55) 1.000
 Hemoglobin <11 g/dL 2 (6) 0 (0) 2 (10) 0.508
 Hemoglobin >16 g/dL 5 (15) 4 (31) 1 (5) 0.066
 Platelets >450 x 103/μL 11 (33) 2 (15) 9 (45) 0.128
 Creatinine clearance <60 mL/min 5 (15) 0 (0) 5 (25) 0.131
  1. RT, radiotherapy; ECOG, Eastern Cooperative Oncology Group; Ig, immunoglobulin; OSM, osteosclerotic myeloma; CD, Castleman’s disease; VEGF, vascular endothelial growth factor; ESR, erythrocyte sedimentation rate.
  2. *The p value was calculated by the Pearson’s Chi-squared test between RT and non-RT.