Clinical and hematologic responses of initial and salvage treatments according to underlying disease types of POEMS syndrome. OSM, osteosclerotic myeloma; CD, Castleman’s disease; VEGFe, vascular endothelial growth factor elevation without gross lesion; Ig, immunoglobulin; CRR, clinical response rate; HRR, hematologic response rate. *In these patients, the clinical symptoms were not improved by chemotherapy. ⁑In these patients, the serum M-protein persisted after chemotherapy. §In these patients, the clinical symptoms and hematologic status were not improved by chemotherapy.