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Table 4 Suggested fractionation regimens for postoperative setting of oral cavity cancers

From: Technical guidelines for head and neck cancer IMRT on behalf of the Italian association of radiation oncology - head and neck working group

Authors   D (Gy) d (Gy) fxs OTT (wks) Comment
Daly et al., [83] CTV2 66 2.2 30 6 For positive margins or ECE
Yao et al., [82]   64-66 2 32-33 6.5 Sequential boost for extracapsular extension, positive or close margins, bone or soft-tissue involvement.
   60 2 30 6  
   63 1.8 30 6  
  CTV3 54 1.8 30 6  
Daly et al., [83]   50.1 1.67 30 6  
   58.1 1.66 35 7  
  1. A surgery-to-RT interval of <6 weeks improves local-regional control.