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Table 4 Characteristics of the six patients with recurrences after optimal hypofractionated conformal radiotherapy

From: Optimal hypofractionated conformal radiotherapy for large brain metastases in patients with high risk factors: a single-institutional prospective study

 

Median (range)

Univariate

Multivariate

p value

p value

HR

95% CI

Age

68.5 (56–82)

0.17

0.20

1.09

0.95-1.25

Sex

M: 3, F: 3

0.91

0.29

0.23

0.01-3.63

Tumor location

Cerebrum (P: 2, F: 2, T: 1, O: 1)

0.85

0.75

1.13

0.53-2.39

Tumor volume (cm3)

18.0 (11.9-24.0)

0.69

0.69

1.04

0.85-1.29

Prescribed isodose (%)

57 (52–66)

0.97

0.73

0.93

0.63-1.37

Fraction number

5 (3–8)

0.89

0.73

0.82

0.27-2.49

SDE of the max. dose (Gy)

48.4 (36.8-54.3)

0.72

0.40

0.85

0.58-1.25

V14 (cm3)

4.9 (3.7-5.1)

0.78

0.90

1.07

0.35-3.32

  1. HR: Hazard ratio, CI: Confidence interval, P: Parietal, F: Frontal, T: Temporal, O: Occipital.