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Table 2 Motion effect on OAR dose distribution in fifteen patients

From: Dynamic simulation of motion effects in IMAT lung SBRT

Constraints Difference between 3D planned dose and cumulative 4D doses Mean (min, max) 4D inter-fraction variation Mean (min, max) Difference between cumulative 4D doses with and without motion Mean (min, max)
Spinal cord    
D max −0.03 Gy (−0.40 Gy, 0.20 Gy) −0.05 Gy (0.00 Gy, 0.40 Gy) −0.03 Gy (−0.30 Gy, 0.50 Gy)
D_ 0.35cc 0.00 Gy (−0.16 Gy, 0.17 Gy) 0.02 Gy (0.00 Gy, 0.05 Gy) 0.03 Gy (−0.12 Gy, 0.24 Gy)
D_ 1.2cc 0.01 Gy (−0.12 Gy, 0.14 Gy) 0.02 Gy (0.00 Gy, 0.06 Gy) 0.03 Gy (−0.13 Gy, 0.18 Gy)
Esophagus    
D max −0.22 Gy (−1.30 Gy, 0.30 Gy) −0.19 Gy (0.00 Gy, 0.80 Gy) −0.37 Gy(−2.60 Gy, 0.30 Gy)
D_ 5cc −0.06 Gy (−0.83 Gy, 1.37 Gy) 0.07 Gy (0.01 Gy, 0.21 Gy) −0.16 Gy (−0.89 Gy, 0.30 Gy)
Heart    
D max −0.51 Gy (−2.00 Gy, 0.90 Gy) 0.27 Gy (0.00 Gy, 0.80 Gy) −0.63 Gy (−2.5 Gy, 0.90 Gy)
D_ 15cc −0.18 Gy (−0.69 Gy, 0.92 Gy) 0.08 Gy (0.00 Gy, 0.23 Gy) −0.38 Gy (−1.54 Gy, 0.33 Gy)
Great vessels    
D max −0.52 Gy (−1.80 Gy, 6.00 Gy) 0.19 Gy (0.00 Gy, 0.40 Gy) 0.39 Gy (−1.10 Gy, 2.00 Gy)
D_ 10cc −0.12 Gy (−2.44 Gy, 2.66 Gy) 0.04 Gy (0.00 Gy, 0.13 Gy) −0.03 Gy (−1.05 Gy, 0.63 Gy)
Trachea    
D max 0.04 Gy (−2.10 Gy, 1.40 Gy) 0.03 Gy (0.00 Gy, 0.40 Gy) 0.13 Gy (0.00 Gy, 1.00 Gy)
D_ 10cc −0.01 Gy (−0.42 Gy, 0.19 Gy) 0.03 Gy (0.00 Gy, 0.37 Gy) 0.01 Gy (−0.08 Gy, 0.14 Gy)
Bronchus    
D max 0.25 Gy (−2.00 Gy, 4.90 Gy) 0.37 Gy (0.00 Gy, 1.20 Gy) 0.75 Gy (−2.00 Gy, 7.80 Gy)
D_ 10cc −0.42 Gy (−4.10 Gy, 2.98 Gy) 0.08 Gy (0.00 Gy, 0.25 Gy) 0.30 Gy (−0.40 Gy, 1.59 Gy)
Rib    
D max −0.58 Gy (−3.00 Gy, 1.50 Gy) 0.29 Gy (0.00 Gy, 1.20 Gy) −0.54 Gy (−1.50 Gy, 0.60 Gy)
D_ 1cc −0.19 Gy (−1.58 Gy, 4.64 Gy) 0.10 Gy (0.01 Gy, 0.32 Gy) −0.33 Gy (−0.99 Gy, 0.44 Gy)
Total lung    
V_ 20Gy 0.02% (−0.87%, 0.66%) 0.02% (0.00%, 0.14%) −0.08% (−0.41% 0.15%)
D_ 1500cc −0.03 Gy (−0.23 Gy, 0.64 Gy) 0.01 Gy (0.00 Gy, 0.09 Gy) 0.03 Gy (−0.13 Gy, 0.74 Gy)
D_ 1000cc −0.03 Gy (−0.18 Gy, 0.16 Gy) 0.00 Gy (0.00 Gy, 0.02 Gy) 0.03 Gy (−0.09 Gy, 0.46 Gy)
  1. The mean value are cumulative dose differences averaged over all patients. The mean values of the 4D inter-fraction variation are the average values of the largest variations among four fractions over all patients.