Table 1 Microarray gene expression changes relative to irradiated HeLa cells (X-ray irradiation plus ART vs. X-ray irradiation alone)
Gene name | Fold change upregulated | Chromosome | Description |
|---|---|---|---|
IMAA | 14.44 | chr16 | SLC7A5 pseudogene |
HSUP1 | 10.05 | chr20 | Similar to RPE-spondin |
FLJ11021 | 9.10 | chr12 | Similar to splicing factor, arginine/serine-rich 4 |
KIAA1904 | 8.98 | chr22 | KIAA1904 protein |
ZRF1 | 8.95 | chr7 | Zuotin related factor 1 |
SDCCAG10 | 8.61 | chr5 | Serologically defined colon cancer antigen 10 |
LOC442573 | 8.47 | chr7 | Similar to postmeiotic segregation increased 2-like 2 |
EIF3S10 | 8.42 | chr10 | Eukaryotic translation initiation factor 3, subunit 10 theta |
KTN1 | 8.34 | chr14 | Kinectin 1 (kinesin receptor) |
LOC642617 | 8.23 | chr2 | Hypothetical protein LOC642617 |
LOC340089 | 7.98 | chr5 | Similar to nuclear pore membrane protein 121 |
GPR18 | 7.97 | chr13 | G protein-coupled receptor 18 |
LOC646074 | 7.93 | chr22 | Similar to nuclear pore membrane protein 121 |
NOL8 | 7.71 | chr9 | Nucleolar protein 8 |
AHNAK | 7.26 | chr11 | AHNAK nucleoprotein (desmoyokin) |
N/A | 7.16 | chr3 | Homo sapiens cDNA clone MGC:99509 IMAGE:3939369 |
GOLGA4 | 7.10 | chr3 | Golgi autoantigen, golgin subfamily a, 4 |
LOC646316 | 6.95 | chr4 | Similar to Telomeric repeat binding factor 1 interacting protein 2) |
CENPF | 6.92 | chr1 | Centromere protein F, 350/400Â ka (mitosin) |
LOC643211 | 6.91 | chr2 | Hypothetical protein LOC643211 |
Gene name | Fold change downregulated | Chromosome | Description |
HBB | 116.84356 | chr11 | Hemoglobin, beta |
HBB | 110.22069 | chr11 | Hemoglobin, beta |
IGHG1 | 93.40286 | chr14 | Immunoglobulin heavy constant gamma 1 (G1m marker) |
N/A | 60.31211 | chr2 | Anti-rabies SOJA immunoglobulin kappa light chain mRNA |
IGHG1 | 59.625664 | chr14 | Immunoglobulin heavy constant gamma 1 (G1m marker) |
IGKC | 56.961563 | chr2 | Immunoglobulin kappa constant |
IGKC | 50.49672 | chr2 | Immunoglobulin kappa constant |
HBD | 43.09641 | chr11 | Hemoglobin, delta |
IGHG1 | 42.666557 | chr14 | Immunoglobulin heavy constant gamma 1 (G1m marker) |
IGHG1 | 40.846592 | chr14 | Immunoglobulin heavy constant gamma 1 (G1m marker) |
IGKC | 37.99056 | chr2 | Immunoglobulin kappa constant |
IGHA1 | 36.901497 | chr14 | Immunoglobulin heavy constant alpha 1 |
IGKC | 34.52912 | chr2 | Immunoglobulin kappa constant |
IGLV3-25 | 28.34214 | chr22 | Immunoglobulin lambda variable 3-25 |
PLUNC | 25.71026 | chr20 | Palate, lung and nasal epithelium carcinoma associated |
IGLV3-25 | 25.19829 | chr22 | Immunoglobulin lambda variable 3-25 |
LOC652848 | 24.885628 | chr14 | Similar to Ig heavy chain V-II region ARH-77 precursor |
N/A | 19.36516 | chr2 | Homo sapiens cDNA clone MGC:104455 IMAGE:30352955 |
N/A | 19.346416 | chr22 | Homo sapiens cDNA clone MGC:71261 IMAGE:4576612 |
IGHG1 | 17.280687 | chr14 | Immunoglobulin heavy constant gamma 1 (G1m marker) |