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Table 5 Cox proportional hazards regression analysis for time to radiation pneumonitis symptoms (N = 100)

From: Pre-radiotherapy FDG PET predicts radiation pneumonitis in lung cancer

Predictor Coefficient SE Hazard ratio (95% CI) p-value
SUV95a 0.18 0.057 1.2 (1.1-1.3) <0.002
Ageb 0.34 0.14 1.4 (1.1-1.8) 0.013
V30 0.05 0.02 1.1 (1–1.1) 0.011
  1. aScaled by 10.
  2. bStandardized age was used with origin corresponding to the mean of 64.
  3. Note: SE = standard error of the estimated coefficient parameter; CI = confidence interval for the hazard ratio; Stepwise backward model selection based on generalized Akaike information criterion was used; symptomatic radiation pneumonitis was conditionally independent of tumor location, stage, histology, smoking status, treatment type, and MLD in the presence of SUV95, V30, and age; p-values derived from two-sided hypothesis tests using Wald chi-square; the rate of symptom development was increased significantly with SUV95, V30, and age.