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Table 4 Multiple logistic regression analysis for grade ≥ 2 RP (N = 100)

From: Pre-radiotherapy FDG PET predicts radiation pneumonitis in lung cancer

Predictor

Coefficient

SE

Odds ratio (95% CI)

p-value

Intercept

-6.1

1.7

  

SUV95a

0.40

0.13

1.5 (1.1-1.9)

<0.0027

Ageb

0.79

0.26

2.2 (1.3-3.7)

<0.0026

V30

0.09

0.034

1.1 (1–1.2)

<0.007

  1. aScaled by 10.
  2. bStandardized age was used with origin corresponding to the mean of 64.
  3. Note: SE = standard error of the estimated coefficient parameter; CI = confidence interval for the odds ratio; Stepwise backward model selection based on Akaike information criterion was used; Symptomatic radiation pneumonitis was conditionally independent of tumor location, stage, histology, smoking status, MLD, and RT modality in the presence of SUV95, V30, and age; p-values derived from two-sided hypothesis tests using Wald chi-square; significant partial effects suggest that the odds of symptomatic radiation pneumonitis increased with SUV95, V30, and age; Nagelkerke coefficient of multiple determination R2 = 0.32.