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Table 3 Logistic regression analysis for grade ≥ 2 RP

From: Pre-radiotherapy FDG PET predicts radiation pneumonitis in lung cancer

Predictor Coefficient SE Odds ratio (95% CI) p-value
SUVmax 0.16 0.095 1.2 (0.97, 1.4) 0.10
SUVmean 0.34 0.15 1.4 (1.1, 1.9) <0.02 a,b
SUVSD1 1.5 0.54 4.4 (1.5, 12.8) <0.0057 a,b
SUV801 0.31 0.13 1.4 (1.1, 1.7) <0.013 a,b
SUV901 0.33 0.12 1.4 (1.1, 1.7) <0.0061 a,b
SUV951 0.33 0.12 1.4 (1.1, 1.7) <0.0049 a,b
HUmax2 0.013 0.02 1 (0.97, 1.1) 0.51
HUmean2 -0.09 0.34 0.91 (0.47, 1.8) 0.79
HUsd2 -0.18 0.93 0.83 (0.14, 5.1) 0.85
HU802 -0.07 0.37 0.93 (0.46, 1.9) 0.85
HU902 -0.10 0.32 0.91 (0.48, 1.7) 0.76
HU952 -0.10 0.32 0.91 (0.48, 1.7) 0.76
MLD3 0.88 0.58 2.4 (0.78, 7.5) 0.13
V53 0.15 0.53 1.2 (0.41, 3.3) 0.77
V103 0.58 0.55 1.8 (0.6, 5.3) 0.30
V203 1.1 0.63 3 (0.87, 10.5) 0.081
V303 1.2 0.57 3.3 (1.1, 10.3) 0.035
FEV1(%)2 -0.13 1 0.88 (0.12, 6.6) 0.897
DLCO(%)2 -1.2 1.1 0.31 (0.034, 2.9) 0.31
  1. 1Scaled by 10.
  2. 2Scaled by 0.01.
  3. 3Log-transformation applied to improve model fit.
  4. aSequentially rejective Bonferroni method applied to adjust for multiplicity at the α = 0.05 familywise significance level.
  5. bOdds of grade ≥ 2 radiation pneumonitis increased with SUVmean, SUVSD, SUV80, SUV90, and SUV95.
  6. Note: SE = standard error of the estimated coefficient parameter; CI = confidence interval for the odds ratio; p-values derived from two-sided hypothesis tests using Wald chi-square.