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Table 3 The outcome of NPC treated by 2D technique and IMRT-SIB in epidemic areas

From: Intensity-modulated radiotherapy with simultaneous integrated boost for locoregionally advanced nasopharyngeal carcinoma

Author and era

No of pts

Stage

Treatment technique

CCRT

OS %

PFS %

DMFS %

Lee 2005 [21]

2,687

I-IVB

2D

14% CCRT, 9% seq

75

63

81

Yeh 2005 [22]

849

I-IVB

2D

No

59

52

74.7

Yi 200 6 [23]

905

I-IVB

2D

2.8% seq

76.1

58.4

79.8

Lin 2010 [24]

370

IIB-IVB

IMRT

Seq without CCRT

89 (3 yr)

81(3 yr) *

86(3 yr)

Wang 2013 [25]

300

I-IVB

IMRT

Stage III/IV with CCRT

86.1 (4 yr)

NA

85.0

Su 2011 [26]

865

I-IVB

IMRT

222 with CCRT

83.0

NA

84.0

This study

271

III-IVB

IMRT

142 with CCRT

79.4

63.9*

79.6

  1. CCRT: Concurrent chemoradiotherapy; OS: Overall survival; PFS: Progression-free survival.
  2. *: Disease-free survival; Seq: Sequential, 2D: Two dimension; IMRT: Intensity-modulated radiotherapy.