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Table 3 The outcome of NPC treated by 2D technique and IMRT-SIB in epidemic areas

From: Intensity-modulated radiotherapy with simultaneous integrated boost for locoregionally advanced nasopharyngeal carcinoma

Author and era No of pts Stage Treatment technique CCRT OS % PFS % DMFS %
Lee 2005 [21] 2,687 I-IVB 2D 14% CCRT, 9% seq 75 63 81
Yeh 2005 [22] 849 I-IVB 2D No 59 52 74.7
Yi 200 6 [23] 905 I-IVB 2D 2.8% seq 76.1 58.4 79.8
Lin 2010 [24] 370 IIB-IVB IMRT Seq without CCRT 89 (3 yr) 81(3 yr) * 86(3 yr)
Wang 2013 [25] 300 I-IVB IMRT Stage III/IV with CCRT 86.1 (4 yr) NA 85.0
Su 2011 [26] 865 I-IVB IMRT 222 with CCRT 83.0 NA 84.0
This study 271 III-IVB IMRT 142 with CCRT 79.4 63.9* 79.6
  1. CCRT: Concurrent chemoradiotherapy; OS: Overall survival; PFS: Progression-free survival.
  2. *: Disease-free survival; Seq: Sequential, 2D: Two dimension; IMRT: Intensity-modulated radiotherapy.