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Table 6 Comparison of PSA kinetics between SBRT and CF-EBRT by pre-treatment PSA (probability values)

From: Hypofractionated SBRT versus conventionally fractionated EBRT for prostate cancer: comparison of PSA slope and nadir

   

Pretreatment PSA (ng/mL)

 
  

≤10

>10

>4

 

Through year

   

Nadir PSA (ng/mL)

    
 

1

ns

ns

ns

 

2

p = 0.001

ns

p = 0.002

 

3

p = 0.005

ns

p = 0.001

Time to Nadir PSA (mos.)

    
 

1

ns

ns

ns

 

2

ns

ns

ns

 

3

p = 0.04

p = 0.03

p = 0.01

Rate of PSA change: ng/mL/Month

   
 

1

ns

ns

ns

 

2

p = 0.05

ns

(p = 0.08)

 

3

(p = 0.06)

ns

p = 0.02

  1. For each of the 3 pretreatment PSA subsets the PSA outcomes were compared between SBRT and CF-EBRT. The distributions for PSA nadir and PSA slope were compared using the Mann–Whitney test. The distributions for the time to PSA nadir was compared using the log rank test.