Figure 2
From: Visualization, imaging and new preclinical diagnostics in radiation oncology
Representative morphological and diffusion-weighted images of an athymic rat bearing a subcutaneous HNSCC (head and neck squamous cell carcinoma) over the left lateral flank. (I.) T1-weighted flash 3D morphological image of an athymic rat bearing a subcutaneous HNSCC (head and neck squamous cell carcinoma) over the left lateral flank for anatomical correlation (white arrow). (II.) Example of a voxel-wise analysis of diffusion weighted images using the bi-exponential IVIM-model. Initial T2-weighted image is shown in (a), (b)-(c) depict the calculated parameter maps for tissue diffusivity D (b), perfusion fraction f (c) and pseudo diffusivity D*(d). Reduced values for f towards the center of the tumor indicate a local decrease in perfusion.