Figure 1

Representative axial T1 weighted TWIST image of an athymic rat bearing a subcutaneous colon carcinoma xenograft over the left flank. (a) Representative axial T1 weighted TWIST image of an athymic rat bearing a subcutaneous colon carcinoma xenograft over the left flank with the arterial input function (AIF) measured in the inferior vena cava as well as the signal enhancement curve over the tumor. (b) Representative quantitative parameter maps depicting different parameters of tumor microcirculation (from top to bottom): plasma volume (%), plasma flow (ml/100 ml/min), plasma mean transit time (s), permeability surface area product (ml/100 ml/min).