Skip to main content

Table 2 Univariate and multivariate analysis of the effect of prognostic factors on OS in patients with resectable SCLC

From: Risk factors for brain metastases in completely resected small cell lung cancer: a retrospective study to identify patients most likely to benefit from prophylactic cranial irradiation

Factors

Univariate analysis

Multivariate analysis

2y-OS %

5y-OS %

X 2

p

HR

95% CI

p

Gender

       

Male

63.0

48.4

     

Female

64.0

43.6

0.015

0.901

   

Age, years

       

<65

64.8

53.3

     

≥65

58.9

32.2

3.079

0.079

1.798

1.027 ~ 3.148

0.040

KPS score

       

≥80

71.5

56.9

     

<80

61.5

42.3

3.487

0.062

1.149

0.631 ~ 2.092

0.649

Smoking status

       

Yes

62.1

52.0

     

No

64.7

42.3

0.284

0.594

   

P-stage

       

I

87.1

74.4

     

II

78.6

61.7

     

III

42.6

26.6

28.70

0.001

2.093

1.399 ~ 3.132

0.001

LVI

       

Yes

48.6

34.1

     

No

67.6

51.8

3.358

0.067

0.935

0.507 ~ 1.723

0.829

PORT

       

Yes

64.7

43.6

     

No

63.0

48.2

0.028

0.866

   

Cycle of ChT

       

<4

61.9

57.1

     

≥4

63.5

46.0

0.221

0.638

   

Brain metastasis

       

Yes

42.9

15.5

     

No

69.0

56.2

14.65

0.001

2.092

1.049 ~ 4.170

0.031

  1. Abbreviations: OS = overall survival; SCLC = small cell lung cancer; 2y-OS = overall survival rate at 2 years; 5y-OS = overall survival rate at 5 years; HR = hazard ratio; CI = confidence interval KPS = Karnofsky performance status; P-stage = pathologic stage; LVI = lymphovascular invasion; PORT = postoperative radiotherapy; ChT = chemotherapy.
Back to article page

Radiation Oncology

ISSN: 1748-717X

Contact us