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Table 4 Univariateand multivariate analysis for prognostic factors on overall survival

From: Trimodality bladder-sparing approach without neoadjuvant chemotherapy for node-negative localized muscle-invasive urinary bladder cancer resulted in comparable cystectomy-free survival

Univariate analysis
  Hazard ratio 95% confidence interval P value
Male gender 0.730 0.327-1.627 0.442
Age, years 1.035 1.001-1.069 0.039
History of TURBT 0.986 0.465-2.087 0.971
ECOG performance status 3.182 1.388-7.291 0.006
Comorbidities 2.264 0.929-5.513 0.072
Clinical T stage 1.565 1.010-2.421 0.045
Hydronephrosis 1.825 0.901-3.692 0.095
RT duration, days 1.016 0.991-1.041 0.196
Concurrent chemotherapy 0.587 0.271-1.268 0.175
Prescribed doses to bladder tumor bed, Gy 0.914 0.858-0.972 0.005
Prescribed doses to whole bladder, Gy 1.001 0.999-1.001 0.245
Complete response (CR) 0.155 0.066-0.358 <0.001
Multivariate analysis
Age 1.064 1.023-1.107 0.002
Performance status 2.840 1.133-7.119 0.026
Complete response (CR) 0.098 0.040-0.240 <0.001