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Figure 1 | Radiation Oncology

Figure 1

From: BAY 87–2243, a novel inhibitor of hypoxia-induced gene activation, improves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts

Figure 1

BAY-87-2243 inhibits nuclear HIF-1α protein expression. UT-SCC-5 tumors were treated either with BAY-87-2243 or carrier for 3, 5, or 7 days and were excised 24 h after end of treatment: a) immunohistochemistry, black arrows indicate the positive nuclear HIF-1α staining, scale bar: 20 μm; b) western blots of nuclear HIF-1α from different animals 3 days after BAY-87-2243 application; c) quantification of western blots by densitometry relative to histone-H2B, means ± SD.

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Radiation Oncology

ISSN: 1748-717X

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