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Table 2 Quantitative comparison of dose conformality and homogeneity

From: A single-field integrated boost treatment planning technique for spot scanning proton therapy

  COIN INH
  SFUD SFIB IMPT SFUD SFIB IMPT
Patient 1       
PTV1 0.507 0.867 0.827 0.021 0.063 0.058
PTV2 0.422 0.857 0.893 - -  
Patient 2       
PTV1 0.771 0.771 - 0.066 0.056 -
PTV2 0.539 0.577 - - - -
PTV3 0.026 0.033 - - - -
Patient 3       
PTV1 0.859 0.910 0.851 0.043 0.038 0.057
PTV2 0.140 0.159 0.154 - -  
Patient 4       
PTV1 0.273 0.427 0.453 0.062 0.089 0.091
PTV2 0.474 0.613 0.638 - -  
PTV3 0.608 0.633 0.613 - -  
Mean ± SD (All patients) 0.435 ± 0.239* 0.585 ± 0.300* - 0.048 ± 0.021 0.062 ± 0.021 -
Mean ± SD (exclude patient 2) 0.469 ± 0.232 0.638 ± 0.274 0.633 ± 0.263 0.042 ± 0.021 0.063 ± 0.026 0.069 ± 0.019
  1. Abbreviations: COIN conformal index, INH inhomogeneity index, PTV planning target volume, SFIB single-field integrated boost, SFUD single field uniform dose, IMPT intensity modulated proton therapy, SD standard deviation. *p < 0.01, Wilcoxon matched-pairs signed rank test.