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Table 2 Quantitative comparison of dose conformality and homogeneity

From: A single-field integrated boost treatment planning technique for spot scanning proton therapy

 

COIN

INH

 

SFUD

SFIB

IMPT

SFUD

SFIB

IMPT

Patient 1

      

PTV1

0.507

0.867

0.827

0.021

0.063

0.058

PTV2

0.422

0.857

0.893

-

-

 

Patient 2

      

PTV1

0.771

0.771

-

0.066

0.056

-

PTV2

0.539

0.577

-

-

-

-

PTV3

0.026

0.033

-

-

-

-

Patient 3

      

PTV1

0.859

0.910

0.851

0.043

0.038

0.057

PTV2

0.140

0.159

0.154

-

-

 

Patient 4

      

PTV1

0.273

0.427

0.453

0.062

0.089

0.091

PTV2

0.474

0.613

0.638

-

-

 

PTV3

0.608

0.633

0.613

-

-

 

Mean ± SD (All patients)

0.435 ± 0.239*

0.585 ± 0.300*

-

0.048 ± 0.021

0.062 ± 0.021

-

Mean ± SD (exclude patient 2)

0.469 ± 0.232

0.638 ± 0.274

0.633 ± 0.263

0.042 ± 0.021

0.063 ± 0.026

0.069 ± 0.019

  1. Abbreviations: COIN conformal index, INH inhomogeneity index, PTV planning target volume, SFIB single-field integrated boost, SFUD single field uniform dose, IMPT intensity modulated proton therapy, SD standard deviation. *p < 0.01, Wilcoxon matched-pairs signed rank test.