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Figure 1 | Radiation Oncology

Figure 1

From: Range modulation in proton therapy planning: a simple method for mitigating effects of increased relative biological effectiveness at the end-of-range of clinical proton beams

Figure 1

The physical dose for a SOBP composed of four pristine Bragg peaks each separate by 6 mm water equivalent. Applying our illustrative model of increased distal RBE to the individual pristine peaks produces the RBE weighted SOBP. The “range mod” technique mitigates the changes in SOBP plateau flatness, range, and effective dose at the distal edge. Here the modulation is achieved by splitting the SOBP into two parts and shifting one by 3 mm to both smooth out the SOBP and decrease the RBE at the end of the beam.

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