From: Clinical experience of SIB-IMRT in anal cancer and selective literature review
Postoperative IMRT | 2 (8%) |
Definitive IMRT | 23 (82%) |
RT dose | |
Series 1 SIB: 45 Gy SIB | 25 (100%) |
IMRT (25x1.8/1.52 Gy) | |
Series 2 Boost: | |
7x2 = 14 Gy (total: 59 Gy) | 20 (80%) |
7x2.1 = 14.7 Gy (total: 59.7 Gy) | 1 (4%) |
8x1.8 = 14.4 Gy (total: 59.4 Gy) | 1 (4%) |
6x1.8 = 9.8 Gy (total: 55.8 Gy) | 1 (4%) |
5x1.8 = 9 Gy (total: 54 Gy) | 2 (8%) |
Treatment breaks >1 day | 4 (16%) |
Concomitant chemotherapy (5-FU and MMC) | 21 (84%) |
Mean treatment volumes (ccm, range) | |
GTV | 33.2 (6-103) |
PTV38 Gy | 1042.9 (248-3222) |
PTV45 Gy | 1483.3 (482-2874) |
PTV59 Gy | 335.1 (56-666) |