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Table 2 Treatment related parameters

From: Clinical experience of SIB-IMRT in anal cancer and selective literature review

Postoperative IMRT 2 (8%)
Definitive IMRT 23 (82%)
RT dose  
Series 1 SIB: 45 Gy SIB 25 (100%)
IMRT (25x1.8/1.52 Gy)  
Series 2 Boost:  
7x2 = 14 Gy (total: 59 Gy) 20 (80%)
7x2.1 = 14.7 Gy (total: 59.7 Gy) 1 (4%)
8x1.8 = 14.4 Gy (total: 59.4 Gy) 1 (4%)
6x1.8 = 9.8 Gy (total: 55.8 Gy) 1 (4%)
5x1.8 = 9 Gy (total: 54 Gy) 2 (8%)
Treatment breaks >1 day 4 (16%)
Concomitant chemotherapy (5-FU and MMC) 21 (84%)
Mean treatment volumes (ccm, range)  
GTV 33.2 (6-103)
PTV38 Gy 1042.9 (248-3222)
PTV45 Gy 1483.3 (482-2874)
PTV59 Gy 335.1 (56-666)
  1. IMRT: intensity modulated radiotherapy, SIB: simultaneously integrated boost, GTV: gross tumor volume, PTV: planning target volume.