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Table 2 Treatment related parameters

From: Clinical experience of SIB-IMRT in anal cancer and selective literature review

Postoperative IMRT

2 (8%)

Definitive IMRT

23 (82%)

RT dose

 

Series 1 SIB: 45 Gy SIB

25 (100%)

IMRT (25x1.8/1.52 Gy)

 

Series 2 Boost:

 

7x2 = 14 Gy (total: 59 Gy)

20 (80%)

7x2.1 = 14.7 Gy (total: 59.7 Gy)

1 (4%)

8x1.8 = 14.4 Gy (total: 59.4 Gy)

1 (4%)

6x1.8 = 9.8 Gy (total: 55.8 Gy)

1 (4%)

5x1.8 = 9 Gy (total: 54 Gy)

2 (8%)

Treatment breaks >1 day

4 (16%)

Concomitant chemotherapy (5-FU and MMC)

21 (84%)

Mean treatment volumes (ccm, range)

 

GTV

33.2 (6-103)

PTV38 Gy

1042.9 (248-3222)

PTV45 Gy

1483.3 (482-2874)

PTV59 Gy

335.1 (56-666)

  1. IMRT: intensity modulated radiotherapy, SIB: simultaneously integrated boost, GTV: gross tumor volume, PTV: planning target volume.