Table 4 Evaluation of frequent side effect before/during/after ART and at timepoint of evaluation in 43 patients from 46 adjuvant radiotherapies

Constipation

Before ART

4/46 (8.7%)

4/4 (100%) grade 1

During ART

6/46 (13.0%)

6/6 (100%) grade 1

After ART¹

6/46 (13.0%)

6/6 (100%) grade 1

Latest follow up²

5/37 (13.5%)

5/5 (100%) grade 1

Diarrhea

Before ART

4/46 (8.7%)

4/4 (100%) grade 1

During ART

20/46 (43.5%)

15/20 (75.0%) grade 1/5/20 (25.0%) grade 2

After ART¹

11/46 (23.9%)

11/11 (100%) grade 1

Latest follow up²

4/37 (10.8%)

4/4 (100%) grade 1

Rectal bleeding

Before ART

3/46 (6.5%)

3/3 (100%) grade 1

During ART

2/46 (4.3%)

2/2 (100%) grade 1

After ART¹

2/46 (4.3%)

2/2 (100%) grade 1

Latest follow up²

1/37 (2.7%)

1/1 (100%) grade 1

Nausea/Vomiting

Before ART

0/46 (0.0%)

-

During ART

4/46 (8.7%)

4/4 (100%) grade 1

After ART¹

0/46 (0.0%)

-

Latest follow up²

0/37 (0.0%)

-

Haematuria

Before ART

2/46 (4.3%)

2/2 (100%) grade 1

During ART

6/46 (13.0%)

6/6 (100%) grade 1

After ART¹

4/46 (8.7%)

4/4 (100%) grade 1

Latest follow up²

1/37 (2.7%)

1/1 (100%) grade 1

Urinary incontinence

Before ART

14/46 (30.4%)

12/14 (85.7%) grade 1/2/14 (14.3%) grade 2

During ART

17/46 (36.9%)

8/17 (47.1%) grade 1/9/17 (52.9%) grade 2

After ART¹

16/46 (34.7%)

9/16 (56.3%) grade 1/7/16 (43.7%) grade 2

Latest follow up²

14/37 (37.8%)

10/14 (71.4%) grade 1/4/14 (28.6%) grade 2

Dysuria (urgency, feeling of obstruction, pain)

Before ART

4/46 (8.7%)

4/4 (100%) grade 1

During ART

7/46 (15.2%)

7/7 (100%) grade 1

After ART¹

5/46 (10.9%)

5/5 (100%) grade 1

Latest follow up²

4/37 (10.8%)

4/4 (100%) grade 1

Skin Erythema in radiated region

Before ART

0/46 (0.0.%)

-

During ART

13/46 (28.3%)

13/13 (100%) grade 1

After ART¹

9/46 (19.6%)

6/9 (66.7%) grade 1/3/9 (33.3%) grade 2

Latest follow up²

1/37 (2.7%)

1/1 (100%) grade 1

Skin hyperpigmentation in radiated region

Before ART

0/46 (0.0.%)

-

During ART

0/46 (0.0.%)

-

After ART¹

6/46 (13.0%)

6/6 (100%) grad 1

Latest follow up²

3/37 (8.1%)

3/3 (100%) grade 1

Lymphedema extremity

Before ART

5/46 (10.9%)

5/5 (100%) grade 1

During ART

6/46 (13.0%)

6/6 (100%) grade 1

After ART¹

6/46 (13.0%)

6/6 (100%) grade 1

Latest follow up²

5/37 (13.5%)

5/5 (100%) grade 1

Lymphocele

Before ART

2/46 (4.3%)

2/2 (100%) grade 1

During ART

3/46 (6.5%)

2/3 (66.7%) grade1/1/3 (33.3%) grade 2

After ART¹

2/46 (4.3%)

2/2 (100%) grade 1

Latest follow up²

0/37 (0.0.%)

-

Paresthesia

Before ART

4/46 (8.7%)

4/4 (100%) grade 1

During ART

5/46 (10.9%)

5/5 (100%) grade 1

After ART¹

5/46 (10.9%)

5/5 (100%) grade 1

Latest follow up²

5/37 (13.5%)

5/5 (100%) grade 1

Fatigue/exhaustion

Before ART

10/46 (21.7%)

10/10 (100%)

During ART

17/46 (37.0%)

17/17 (100%)

After ART¹

16/46 (34.8%)

16/16 (100%)

Latest follow up²

9/37 (24.3%)

9/9 (100%)

Thrombosis

Before ART

0/46 (0.0.%)

-

During ART

0/46 (0.0.%)

-

After ART¹

0/46 (0.0.%)

-

Latest follow up²

0/37 (0.0.%)

-

Embolism

Before ART

0/46 (0.0.%)

-

During ART

0/46 (0.0.%)

-

After ART¹

0/46 (0.0.%)

-

Latest follow up²

0/37 (0.0.%)

-