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Table 2 Normal tissue dosimetric comparison of stereotactic body radiation therapy and intracavitary brachytherapy

From: Dosimetric feasibility of stereotactic body radiation therapy as an alternative to brachytherapy for definitive treatment of medically inoperable early stage endometrial cancer

Site Volume Tolerance limit Mean dose (Gy, per fx) ± SD p-value
I-BT SBRT
Bladder      
  D50% 4.25 2.04 ± 0.78 1.76 ± 1.08 NS
  D10% 7.65 3.73 ± 1.44 3.65 ± 1.37 NS
  D0.1 cc - 6.44 ± 3.05 5.55 ± 1.46 NS
  D1 cc 8.93 5.22 ± 2.27 4.76 ± 1.48 NS
  D2 cc 4.60 4.68 ± 2.02 4.34 ± 1.51 NS
Rectum      
  D50% 4.25 0.83 ± 0.37 1.20 ± 0.63 NS
  D20% 6.80 1.27 ± 0.85 2.25 ± 0.76 NS
  D10% 7.65 1.56 ± 1.21 2.65 ± 0.75 NS
  D0.1 cc - 2.64 ± 2.68 4.25 ± 1.25 NS
  D1 cc 8.93 2.14 ± 1.98 3.37 ± 0.80 NS
  D2 cc 4.60 1.91 ± 1.65 3.07 ± 0.74 NS
  D20 cc 6.50 0.93 ± 0.50 1.40 ± 0.84 NS
Sigmoid      
  D0.1 cc - 5.41 ± 1.66 5.77 ± 0.52 NS
  D2 cc 4.80 4.05 ± 1.18 4.48 ± 0.49 NS
  D20 cc 6.50 1.73 ± 0.82 2.65 ± 0.78 0.02
Other bowel      
  D0.1 cc - 3.49 ± 1.43 6.69 ± 0.55 <0.005
  D2 cc - 2.66 ± 1.11 5.56 ± 0.45 <0.005
  D5 cc 4.75 2.28 ± 0.99 5.03 ± 0.46 <0.005
  D20 cc 6.50 1.51 ± 0.64 3.94 ± 0.62 <0.005
Femoral Heads      
  Max 6.89 0.83 ± 0.22 2.83 ± 1.22 <0.005
  D10 cc 4.59 0.57 ± 0.15 2.22 ± 1.09 <0.005
  1. Abbreviations: SD standard deviation, I-BT intracavitary brachytherapy, SBRT stereotactic body radiation therapy, fx fraction, V(x)% the percentage volume of the structure receiving x percent of the prescription dose of 8.5Gy, D(x)% the highest dose received by x percent of the volume, NS non-significant.