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Table 2 The most frequent moderately-late side effects recorded

From: IMRT sparing of normal tissues in locoregional treatment of breast cancer

Moderately-late side effects

Adverse events

Grade

Baseline

3 months

6 months

12 months

18 months

24 months

30 months

30 pts

30 pts

30 pts

29 pts

28 pts

27 pts

26 pts

Erythema pigmentation

Grade 0

 

6

14

18

22

23

22

Grade1

 

23

16

11

6

4

4

Grade2

 

1

0

0

0

0

0

Induration fibrosis

Grade 0

 

23

23

22

24

23

22

Grade 1

 

6

6

7

4

4

4

Grade 2

 

1

1

0

0

0

0

Telangiectasia

Grade 0

 

30

30

29

26

23

21

 

Grade 1

 

0

0

0

2

4

4

 

Grade 2

 

0

0

0

0

0

1

Breast/chest wall pain

Grade 0

23

13

16

17

18

20

20

Grade 1

6

16

13

12

9

6

6

Grade 2

1

0

1

0

1

1

0

Grade 3

0

1

0

0

0

0

0

Cough/dyspnea

Grade 0

27

28

28

26

25

26

26

Grade 1

3

2

2

3

2

1

0

MSK upper limb treated/neurosensitive symptoms

Grade 0

18

24

25

25

25

25

26

Grade 1

10

5

4

4

3

3

1

Grade 2

2

1

1

0

0

0

0

  1. The only grade 2 reported at 30 months is a cosmetic one. Note that the number of grade 1 toxicity is low at 30 months, with significant decreased number over time for pain and skin erythema/pigmentation.
  2. We can note that the number of grade 1 or 2 side effects for cough/dyspnea and neuro-muscular symptoms are not very significantly different between baseline and early follow-up assessments.
  3. MSK: musculoskeletal.