131I-GMSs | 1d | 4d | 8d | 16d | Â |
---|
 | 43.29 ± 5.27 | 29.28 ± 3.72 | 24.71 ± 7.28 | 19.93 ± 5.24 |  |
Na131I solution | 1Â h | 6Â h | 24Â h | 48Â h | 72Â h |
 | 1.83 ± 0.46 | 0.60 ± 0.29 | 0.45 ± 0.07 | 0.14 ± 0.02 | 0.06 ± 0.01 |
- The comparison of the intratumoral retention of radioactivity after intratumoral injections of 131I-GMSs and Na131I solution.131I-GMSs provided sustained intratumoral retention of injected radioactivity, maintaining 19.93 ± 5.24% of the injected radioactivity within the tumors after 16 days. In contrast, radioactivity was cleared rapidly from the tumors after injection of Na131I solution. By 1 h, the Na131I solution–treated group retained only 1.83 ± 0.46% of the injected radioactivity within the tumors.