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Table 1 Biodistribution after intratumoral injections of 131 I-GMSs (%, mean ± SD)

From: Interventional therapy for human breast cancer in nude mice with 131I gelatin microspheres (131I-GMSs) following intratumoral injection

Time

Liver

Thyroid

Lung

Kidney

Spleen

Bone

Muscle

Serum

Tumor

1 d

0.09 ± 0.03

0.33 ± 0.20

2.67 ± 0.42

0.57 ± 0.34

0.1 ± 0.04

0.51 ± 0.10

0.12 ± 0.07

0.16 ± 0.06

43.29 ± 5.27

4 d

0.07 ± 0.02

0.12 ± 0.05

1.89 ± 0.58

0.69 ± 0.30

0.04 ± 0.01

0.05 ± 0.02

0.02 ± 0.01

0.09 ± 0.01

29.28 ± 3.32

8 d

0.01 ± 0.00

0.02 ± 0.01

0.34 ± 0.25

0.05 ± 0.03

0.06 ± 0.01

0.11 ± 0.03

0.02 ± 0.01

0.04 ± 0.01

24.71 ± 7.28

16 d

< 0.01

0.02 ± 0.00

0.10 ± 0.06

0.02 ± 0.01

0.01 ± 0.00

0.09 ± 0.01

0.02 ± 0.01

0.05 ± 0.01

19.93 ± 5.24

  1. The biodistribution of radioactivity after intratumoral injections of 131I-GMSs. The intratumoral retention of injected radioactivity into the tumors was expressed as the percentage of the injected dose in the whole tumor; tissue concentrations of other organs were expressed as the percentage of the injected dose per gram (% ID)/g, and the radioactivity in the serum was expressed as the percentage of the injected dose per milliliter.