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Table 2 Comparative clinical outcome analysis from brachytherapy series

From: High-dose rate brachytherapy in localized penile cancer: short-term clinical outcome analysis

Authors

Type

n

Dose (Gy)

F/up (months)

LC 5y (%)

CSS 5y (%)

Necrosis (%)

Stenosis (%)

PP (%)

Chaudhary et al. [16]

LDR

23

50

21

70

 

0

9

70

De Crevoisier et al. [12]

LDR

144

65

68

80(10)

92(10)

26

29

72

Crook et al. [17]

LDR/PDR

67

60

48

87

83,6(10)

12

9

88

Delannes et al. [18]

LDR

51

50-65

65

86

85

23

45

75

Kiltie et al. [19]

LDR

31

63.5

61.5

81

85,5

8

44

75

Mazeron et al. [20]

LDR

50

60-70

36-96

78

 

6

19

74

Rozan et al. [15]

LDR

184

63

139

86

88

21

45

78

Soria et al. [14]

LDR

102

61-70

111

77

72

1

1

72

Petera J et al. [11]

HDR

10

54*

20

100 (<2y)

100 (<2y)

0

0

100

Present serie

HDR

12

36/39**

27

83

100

9

9

92

  1. Type: modality of radiation therapy; LDR: Low-dose rate brachytherapy; PDR: Pulse-dose rate brachytherapy; HDR: High-dose rate brachytherapy; n: number of patients; LC: local control; CSS: cause specific survival; F/up: follow-up in months; PP: Penile preservation.
  2. *54 Gy in 18 fractions over 9 days.
  3. **36 Gy in 9 fractions over 5 days (in the adjuvant setting: 6 Gy day 1 + 2 x 3.75 Gy from day 2 to day 5) or 39 Gy in 9 fractions over 5 days (in sole therapy: 7 Gy day 1 + 2 x 4 Gy from day 2 to day 5).