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Table 1 Demographic and treatment characteristics for 818 patients undergoing mastectomy and receiving postmastectomy radiotherapy

From: No difference in dose distribution in organs at risk in postmastectomy radiotherapy with or without breast implant reconstruction

 

Total

IBR+

IBR-

 

Characteristics

n = 818 (%)

n = 162 (%)

n = 656 (%)

P- value¶

Age at mastectomy, years

    

  Median [min-max]

58 [21-90]

45 [21-69]

58 [21-90]

<0.001

  ≤55

363 (44.4)

136 (84.0)

227 (34.6)

 

  >55

455 (55.6)

26 (16.0)

429 (65.4)

<0.001

Calendar year mastectomy

    

  2009

260 (31.8)

61 (37.7)

199 (30.3)

 

  2010

292 (35.7)

47 (29.0)

245 (37.4)

 

  2011

266 (32.5)

54 (33.3)

212 (32.3)

0.093

Side#

    

  Right

391 (47.8)

90 (55.6)

301 (45.9)

 

  Left

427 (52.2)

72 (44.4)

355 (54.1)

0.027

Tumor size

    

  pT1

309 (37.8)

72 (44.4)

237 (36.1)

 

  pT2

333 (40.7)

57 (35.2)

276 (42.1)

 

  pT3

125 (15.3)

25 (15.4)

100 (15.2)

0.15

  Missing*

51 (6.2)

8 (4.9)

43 (6.6)

 

Lymph nodes

    

  pN0

295 (36.1)

83 (51.2)

212 (32.3)

 

  pN+

511 (62.5)

77 (47.5)

434 (66.2)

<0.001

  Missing*

12 (1.5)

2 (1.2)

10 (1.5)

 

Adjuvant chemotherapy

    

  Yes

388 (47.4)

91 (56.2)

297 (45.3)

 

  No

415 (50.7)

70 (43.2)

345 (52.6)

0.020

  Missing*

15 (1.8)

1 (0.6)

14 (2.1)

 

Neoadjuvant chemotherapy

    

  No

559 (68.3)

130 (80.2)

429 (65.4)

 

  Yes

259 (31.7)

32 (19.8)

227 (34.6)

<0.001

Endocrine therapy

    

  Yes

643 (78.6)

110 (67.9)

533 (81.3)

 

  No

164 (20.1)

49 (30.2)

115 (17.5)

<0.001

  Missing*

11 (1.3)

3 (1.9)

8 (1.2)

 

RT target

    

  Chest wall

242 (29.6)

80 (49.4)

162 (24.7)

 

  Chest wall plus lymph nodes

576 (70.4)

82 (50.6)

494 (75.3)

<0.001

Boost dose

    

  Yes

27 (3.3)

3 (1.9)

24 (3.7)

 

  No

791 (96.7)

159 (98.1)

632 (96.3)

0.33

Bolus field

    

  Yes

34 (4.2)

3 (1.9)

31 (4.7)

 

  No

784 (95.8)

159 (98.1)

625 (95.3)

0.12

Breast implant

    

  Permanent expander

92 (56.8)

92 (56.8)

-

 

  Permanent implant

40 (24.7)

40 (24.7)

-

 

  Temporary expander with a magnetic port

30 (18.5)

30 (18.5)

-

-

  1. IBR indicates immediate breast reconstruction; RT, radiotherapy; pT, tumor size.
  2. *Not included into statistical analysis.
  3. #Including eleven patients with bilateral radiotherapy: IBR + (n = 2) and IBR- (n = 9).
  4. ¶Pearson χ2 test.