Table 1 Patient and tumor characteristics by age group (very elderly and younger status)
All | Very elderly ≥ 85 years | Younger < 85 years | p value | |
|---|---|---|---|---|
(n = 81) | (n = 20) | (n = 61) | ||
Age (years) | ||||
Median (range) | 80 (64–93) | 86 (85–93) | 78 (64–84) | |
Gender | 0.002* | |||
Female | 17 | 9 | 8 | |
Male | 64 | 11 | 53 | |
Performance status (ECOG) | 0.44 | |||
0/1/2/3/4 | 55/24/2/0/0 | 14/6/0/0/0 | 41/18/2/0/0 | |
T stage | 0.57 | |||
T1a/T1b/T2a | 42/21/18 | 9/7/4 | 33/14/14 | |
Histology | 0.62 | |||
Adenocarcinoma | 35 | 11 | 24 | |
Squamous cell carcinoma | 27 | 5 | 22 | |
Unclassified NSCLC | 2 | 0 | 2 | |
Unproven | 17 | 4 | 13 | |
Tumor location | 0.64 | |||
Central/Peripheral | 6/75 | 1/19 | 5/56 | |
Tumor opacity | 0.41 | |||
Solid/GGO | 79/2 | 20/0 | 59/2 | |
Operability | 0.49 | |||
Operable/Inoperable | 21/60 | 4/16 | 17/44 | |
Breath-hold | 0.02* | |||
Yes/No | 50/31 | 8/12 | 42/19 | |
Total dose | 0.49 | |||
48 Gy/60 Gy | 60/21 | 16/4 | 44/17 | |
CTV (cc) | 0.92 | |||
Mean ± SD (range) | 19.5 ± 18.5 (1.1–91) | 19.1 ± 19.3 (2.5–68) | 19.7 ± 18.4 (1.1–91) | |
PTV (cc) | 0.46 | |||
Mean ± SD (range) | 69.1 ± 49.7 (9.3–224) | 76.3 ± 65.4 (14.3–224) | 66.8 ± 43.8 (9.3–205) | |
V20 (%) | 0.64 | |||
Mean ± SD (range) | 5.9 ± 3.2 (1.5–16) | 6.2 ± 3.3 (1.6–14.9) | 5.8 ± 3.2 (1.5–16) | |
MLD (Gy) | 0.30 | |||
Mean ± SD (range) | 3.9 ± 1.6 (1.2–9.2) | 4.2 ± 1.5 (1.6–7.6) | 3.8 ± 1.6 (1.2–9.2) |