Table 2 Univariate Cox proportional hazards model predicting androgen deprivation therapy-free survival and progression-free survival

Prognostic group at diagnosis

 Low-Intermediate

1

0.72

1

0.41

 High

0.99 (0.36 – 2.74)

0.78 (0.33 – 1.88)

0.58

 Very high

1.45 (0.48 – 4.4)

1.40 (0.56 – 3.53)

0.47

Interval from diagnosis to metastases (yr)

1 (0.99 – 1.01)

0.51

1 (0.99 – 1.01)

0.55

PSA level at time of metastases (ng/ml)

1 (0.97 – 1.03)

0.96

1 (0.98 – 1.03)

0.67

PSA DT at time of metastases (mo)

0.83 (0.71 – 0.97)

0.02

0.90 (0.82 – 0.99)

0.04

Number of lesions at diagnosis of metastases

1.11 (0.56 – 2.22)

0.75

1.02 (0.53 – 1.94)

0.96

Pattern of metastatic spread

 Minimal

1

0.37

1

0.27

 Extensive

1.48 (0.63 – 3.49)

1.53 (0.72 – 3.2)

Location of metastasis*

 Node

1

0.10

1

0.25

 Bone

2.02 (0.87 – 4.72)

1.54 (0.74 – 3.22)