From: Repeated stereotactic body radiotherapy for oligometastatic prostate cancer recurrence
Characteristics | All patients (n = 50) |
---|---|
Age at diagnosis (yrs) | |
Median (IQR) | 59 (55–62) |
Follow-up from PCa diagnosis (yrs) | |
Median (IQR) | 7.8 (5.3-10.5) |
Primary therapy | |
Radical prostatectomy alone | 6 (12%) |
Radical prostatectomy with postoperative RT | 22 (44%) |
Radical prostatectomy with postoperative RT + ADT | 14 (28%) |
Radiotherapy + ADT | 6 (12%) |
Radiotherapy alone | 2 (4%) |
PSA at initial diagnosis (ng/ml) | |
Mean (range) | 16 (3.5-81) |
Median (IQR) | 10.4 (7–16.9) |
Prognostic grouping | |
Low | 1 (2%) |
Intermediate | 16 (32%) |
High | 19 (38%) |
Very high | 14 (28%) |
Interval from diagnosis to metastases (yr) | |
Mean (range) | 5.3 (0.2 – 15) |
Median (IQR) | 4.8 (2.9 – 7.3) |
PSA level at first documented metastases (ng/ml) | |
Mean (range) | 10.9 (0.2 – 117) |
Median (IQR) | 5.1 (2.0 – 8.6) |
PSA DT at first documented metastases (mo) | |
Mean (range) | 6.0 (1 – 30) |
Median (IQR) | 3.8 (3.0 – 6.9) |
Number of lesions at diagnosis of metastases | |
1 metastasis | 37 (74%) |
2 metastases | 8 (16%) |
3 metastases | 6 (12%) |
Primary site of metastases | |
Lymph nodes | |
Pelvic | 24 (50%) |
Obturator | 1 (2%) |
Internal iliac | 6 (12%) |
External iliac | 10 (20%) |
Presacral | 2 (4%) |
Common iliac | 3 (6%) |
Combination of nodal sites | 2 (4%) |
Extrapelvic | 1 (2%) |
Both | 2 (4%) |
Bones | |
Axial | 8 (16%) |
Appendicular | 11 (22%) |
Both | 3 (6%) |
Viscera | |
Liver | 1 (2%) |
Treatment at time of metastases (%) | |
SBRT 10 × 5 Gy + 1 mo ADT | 35 (70%) |
SBRT 3 × 10 Gy | 15 (30%) |