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Table 4 Analysis of factors predicting local tumor control after 2-session SRS (Fine-Gray proportional hazards model)

From: A minimally invasive treatment option for large metastatic brain tumors: long-term results of two-session Gamma Knife stereotactic radiosurgery

Covariate

Hazard ratio (95% CI)

P value

Prior local treatment

2.48 (0.489-12.5)

0.270

Large tumor volume (> 20 mL)

0.600 (0.119-3.01)

0.530

High cumulative dose (> 30 Gy as D95)

0.261 (0.068-1.01)

0.051

Significant tumor volume decrease at 2nd session

0.087 (0.009-0.832)

0.034

  1. SRS = stereotactic radiosurgery, CI = confidence interval, D95 = the dose 95% of the target volume receives.