A minimally invasive treatment option for large metastatic brain tumors: long-term results of two-session Gamma Knife stereotactic radiosurgery

Table 1 Summary of clinical data from 58 consecutive patients with 61 large BM

Characteristics	Values
Sex (male/female)	37/21
Age (years), median (range)	66 (32–88)
KPS, median (range)	70 (30–100)
Active Extra-CNS disease/Extra-CNS metastasis	45 (76%)
RTOG-RPA class I/class II/class III	3/27/28
Primary cancer
Lung	34
Breast	7
Colon & Rectus	7
Ovary	2
Double cancer	3
Other	5
No. of intracranial lesions, median (range)	2 (1–8)
Tumor location
Supratentorial	41
Infratentorial	20
Procedures prior to SRS
Craniotomy	14
Ommaya reservoir	10
WBRT	4

BM = brain metastases, KPS = Karnofsky performance status, CNS = central nervous system, RTOG-RPA = radiation treatment oncology group recursive partitioning analysis, SRS = stereotactic radiosurgery, WBRT = whole brain radiotherapy.

ISSN: 1748-717X