sHsp70 levels in the serum of SCCHN patients untreated and after therapy. Blood was collected from patients with SCCHN. sHsp70 concentration was measured with ELISA in three independent experiments in duplicates. Standard box plots are shown with boundaries indicating the 25th and the 75th percentile. The line inside boxes indicates the median and the whiskers indicate the 10th and 90th percentile, respectively. All outliers are shown in the graph. (healthy n = 28, before therapy n = 21, during therapy n = 10, follow-up 1st year n = 9, follow-up 2nd year n = 14). The reason for the different n numbers is due to some missing blood samples during the course of disease. (*p < 0.05, ***p < 0.001).